Guide
Nerve Health Guide: What Causes Numbness and Tingling, and Where Neuralisse Fits
Peripheral nerves carry touch, pain and movement signals between your body and brain. The NINDS says more than 100 types of nerve damage exist and diabetes is the leading cause. New numbness, tingling or burning needs a doctor first. Neuralisse is a once-daily supplement for nerve health; it is not a treatment for neuropathy.
Written by the Neuralisse editorial teamUpdated
The basics
What do peripheral nerves do?
Peripheral nerves are the wiring outside your brain and spinal cord. They carry messages to and from your hands, feet, skin, muscles and organs.
Doctors sort these nerves into three groups, and damage shows up differently in each.
Sensory nerves
They report touch, heat, cold, pain and the position of your feet. Damage here often feels like numbness, pins and needles, or burning.
Motor nerves
They tell muscles when to move. Damage can cause weakness, cramps, or trouble lifting the front of the foot.
Autonomic nerves
They run things you do not think about: heart rate, sweating, digestion and blood pressure. Damage can cause dizziness when standing or stomach trouble.
The longest nerves reach the toes, so symptoms often start in the feet.
Causes
What causes numbness, tingling and burning in the feet?
Diabetes is the most common cause, according to the National Institute of Neurological Disorders and Stroke (NINDS, Peripheral neuropathy). The NINDS also says peripheral neuropathy affects millions of people in the U.S. and comes in more than 100 types.
The NIDDK reports that about one-third to one-half of people with diabetes have peripheral neuropathy (NIDDK, Diabetic neuropathy). Many other things can cause the same feelings, so the cause matters more than the symptom.
| Cause | How it can affect nerves |
|---|---|
| Diabetes and prediabetes | High blood sugar over years can injure nerves and the small vessels that feed them |
| Low vitamin B12 | B12 is needed to keep nerve coverings healthy; long-term metformin use can lower it |
| Heavy alcohol use | Alcohol and poor diet together can damage nerves |
| Pressure on a nerve | Carpal tunnel or a pinched nerve in the back can cause tingling in one area |
| Kidney or thyroid problems | Waste buildup or low thyroid hormone can affect nerve function |
| Some medicines | Certain cancer drugs and other medicines list nerve effects |
| Infections and immune conditions | Shingles, HIV, Lyme disease and autoimmune problems can involve nerves |
MedlinePlus puts it simply: tingling or numbness in the hands and feet is a symptom, and treatment goes after the cause (MedlinePlus, Nerve disorders).
Act now
Which nerve symptoms need a doctor right away?
Some nerve symptoms should not wait for a routine visit. Call your doctor the same day, or get emergency care, if you notice any of the signs below.
Sudden numbness or weakness on one side of the body, a drooping face or slurred speech (call 911). Weakness that spreads over hours or days. A foot sore, blister or cut that is not healing, or a red, warm, swollen foot. Loss of bladder or bowel control. Numbness after a fall or a back injury.
Slower changes deserve a visit too. New tingling, burning that wakes you at night, trouble feeling the floor, or new balance problems are all reasons to book an appointment. The NIDDK notes that nerve symptoms in diabetes are often worse at night (NIDDK, Peripheral neuropathy).
Write down when the feeling started, where it is, and whether it affects one side or both.
At the doctor
How do doctors check for nerve damage?
Most nerve checkups start with questions and a hands-on exam; tests follow if more detail is needed.
History
Your doctor asks about symptoms, blood sugar, alcohol, family history, work and every medicine and supplement you use.
Physical and foot exam
A thin nylon thread (monofilament), a tuning fork and a reflex hammer show how well you feel touch and vibration.
Blood tests
Common checks include blood sugar or A1C, vitamin B12, kidney function and thyroid levels.
Nerve tests if needed
Nerve conduction studies and electromyography (EMG) measure how fast and how well nerves send signals.
Daily basics
What daily habits do the NIH and CDC stress for nerve health?
Blood sugar control and daily foot checks top the list. The NIDDK says staying near your blood sugar goals keeps nerve damage from getting worse (NIDDK, Peripheral neuropathy), and MedlinePlus says control can help prevent nerve problems (MedlinePlus, Diabetic nerve problems).
The CDC asks people with diabetes to look at their feet every day. It says early treatment of foot problems greatly lowers the risk of amputation (CDC, Diabetes and your feet).
| Blood sugar | Keep near the goals you set with your care team; take medicines as prescribed |
|---|---|
| Feet | Check every day for cuts, blisters, redness and swelling (CDC, Diabetes and your feet) |
| Foot exam | At least once a year with your health care professional (NIDDK, Peripheral neuropathy) |
The foot care guide turns the CDC advice into a simple daily routine.

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Supplements
Where does a supplement like Neuralisse fit in nerve health?
A supplement can be one small part of a daily routine, after a diagnosis and alongside your care plan. It cannot replace finding the cause, blood sugar control, or foot care.
The label calls Neuralisse a "Nerve Support Formula" for nerve health and comfort support, each marked with the FDA asterisk. It holds 80 mg of magnesium plus a 575 mg blend with alpha-lipoic acid, butcher's broom, L-carnitine, turmeric and coenzyme Q10.
Where it can fit
- One capsule a day, easy to add to a steady routine
- Full ingredient list and the magnesium amount are printed
- Familiar nutrients with public safety data from the NIH
- A 60-day window to decide if it is worth keeping
Where it does not fit
- As a reason to delay a doctor visit for new symptoms
- As a swap for diabetes medicine or foot care
- For anyone under 18, pregnant or nursing (label)
- Without a medicine check if you take diabetes drugs or blood thinners
The NCCIH says never to replace diabetes care with an unproven product (NCCIH, Diabetes and supplements). Read how to judge a nerve support supplement before you buy any brand.
Before you start
Is a nerve support supplement right for you?
Five quick questions sort out who should talk to a doctor first. If any answer is yes, bring the bottle to your next visit before you start.
Your plan
What should you do next about numbness or tingling?
Start with a doctor visit, not a purchase. Once you know the cause, you can decide with your care team whether a supplement adds anything.
- This week
Book a visit for any new or changing symptom. Write down your symptoms and medicines.
- Every day
Check your feet, wear supportive shoes and keep blood sugar near goal if you have diabetes.
- At the visit
Ask about B12, A1C, kidney and thyroid tests, and whether a supplement is safe with your medicines.
FAQ
Nerve health questions people ask
What is the most common cause of numbness in the feet?
Diabetes is the leading cause of peripheral neuropathy in the U.S., according to the NINDS. Low vitamin B12, heavy alcohol use, kidney or thyroid problems, pressure on a nerve and some medicines can cause the same feeling, so a doctor needs to find the cause.
When should I worry about tingling in my feet?
Worry right away if tingling comes on suddenly, affects one side of the body, spreads over hours or days, or comes with weakness, a foot wound or loss of bladder control. Slow, new tingling still needs a routine visit so a doctor can check your blood sugar, B12 and nerves.
Can nerve damage from diabetes get better?
The NIDDK says keeping blood sugar near your goals can keep nerve damage from getting worse. How much feeling returns differs from person to person. Your care team can explain what to expect based on your exam, your A1C and how long symptoms have been present.
What tests check for peripheral neuropathy?
Most checks start with a foot exam using a monofilament and tuning fork, plus blood tests such as A1C and vitamin B12. If more detail is needed, a doctor may order nerve conduction studies and electromyography, which measure how well nerves carry signals.
Can a supplement fix nerve damage?
No supplement is approved by the FDA to treat or repair nerve damage. Some nutrients, such as alpha-lipoic acid, have mixed research for nerve discomfort in diabetes. A supplement may fit a routine, but treatment depends on the cause your doctor finds.
Is Neuralisse a treatment for neuropathy?
No. Neuralisse is a dietary supplement that the label describes for nerve health and comfort support. It is not a drug and is not meant to diagnose, treat, cure or prevent neuropathy, diabetes or any disease.
Who wrote this
Written and reviewed by
Plain-language pages built from the bottle label, the order page and linked public health sources such as NIH, FDA and CDC.
Last updated . Read our editorial standards and how we check reviews. This website is run by an American stocking outlet for Neuralisse, not by the manufacturer. We earn money when you buy through our order links.
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